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The costimulatory molecule DNAM-1 is essential for optimal differentiation of memory natural killer cells during mouse cytomegalovirus infection

Recent studies demonstrate that natural killer (NK) cells have adaptive immune features. Here, we investigated the role of the costimulatory molecule DNAM-1 in the differentiation of NK cells in a mouse model of cytomegalovirus (MCMV) infection. Antibody blockade of DNAM-1 suppressed the expansion o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nabekura, Tsukasa, Kanaya, Minoru, Shibuya, Akira, Fu, Guo, Gascoigne, Nicholas R.J., Lanier, Lewis L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943894/
https://ncbi.nlm.nih.gov/pubmed/24440149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.12.011
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