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The costimulatory molecule DNAM-1 is essential for optimal differentiation of memory natural killer cells during mouse cytomegalovirus infection

Recent studies demonstrate that natural killer (NK) cells have adaptive immune features. Here, we investigated the role of the costimulatory molecule DNAM-1 in the differentiation of NK cells in a mouse model of cytomegalovirus (MCMV) infection. Antibody blockade of DNAM-1 suppressed the expansion o...

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Bibliografiske detaljer
Main Authors: Nabekura, Tsukasa, Kanaya, Minoru, Shibuya, Akira, Fu, Guo, Gascoigne, Nicholas R.J., Lanier, Lewis L.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943894/
https://ncbi.nlm.nih.gov/pubmed/24440149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2013.12.011
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