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FoxA Proteins Regulate H19 Endoderm Enhancer E1 and Exhibit Developmental Changes in Enhancer Binding In Vivo

Multiple enhancers govern developmental and tissue-specific expression of the H19-Igf2 locus, but factors that bind these elements have not been identified. Using chromatin immunoprecipitation, we have found two FoxA binding sites in the H19 E1 enhancer. Mutating these sites diminishes E1 activity i...

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Detalhes bibliográficos
Main Authors: Long, Lingyun, Spear, Brett T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC522251/
https://ncbi.nlm.nih.gov/pubmed/15485926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.21.9601-9609.2004
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