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Paradoxical Role of DNA Methylation in Activation of FoxA2 Gene Expression during Endoderm Development

The transcription factor FoxA2 is a master regulator of endoderm development and pancreatic beta cell gene expression. To elucidate the mechanisms underlying the activation of the FoxA2 gene during differentiation, we have compared the epigenetic status of undifferentiated human embryonic stem cells...

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Detalhes bibliográficos
Main Authors: Bahar Halpern, Keren, Vana, Tal, Walker, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156079/
https://ncbi.nlm.nih.gov/pubmed/25016019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.573469
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