Decoding the dynamic DNA methylation and hydroxymethylation landscapes in endodermal lineage intermediates during pancreatic differentiation of hESC

Dynamic changes in DNA methylation and demethylation reprogram transcriptional outputs to instruct lineage specification during development. Here, we applied an integrative epigenomic approach to unveil DNA (hydroxy)methylation dynamics representing major endodermal lineage intermediates during panc...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Li, Jia, Wu, Xinwei, Zhou, Yubin, Lee, Minjung, Guo, Lei, Han, Wei, Mo, William, Cao, Wen-ming, Sun, Deqiang, Xie, Ruiyu, Huang, Yun
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Gene regulation, Chromatin and Epigenetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5888657/
https://ncbi.nlm.nih.gov/pubmed/29394393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky063
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