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ARF Impedes NPM/B23 Shuttling in an Mdm2-Sensitive Tumor Suppressor Pathway

The ARF tumor suppressor is widely regarded as an upstream activator of p53-dependent growth arrest and apoptosis. However, recent findings indicate that ARF can also regulate the cell cycle in the absence of p53. In search of p53-independent ARF targets, we isolated nucleophosmin (NPM/B23), a prote...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Main Authors: Brady, Suzanne N., Yu, Yue, Maggi, Leonard B., Weber, Jason D.
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2004
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC522235/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15485902/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.21.9327-9338.2004
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