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Pharmacokinetics of Lidocaine Hydrochloride Administered with or without Adrenaline for the Paravertebral Brachial Plexus Block in Dogs

Adrenaline is known to prolong the duration of local anesthesia but its effects on the pharmacokinetic processes of local anesthetic drugs are not fully understood. Our objective was to develop a compartmental model for quantification of adrenaline’s impact on the pharmacokinetics of perineurally-in...

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發表在:PLoS One
Main Authors: Choquette, Amélie, Troncy, Eric, Guillot, Martin, Varin, France, del Castillo, Jérôme R. E.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221883/
https://ncbi.nlm.nih.gov/pubmed/28068408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169745
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