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Pharmacokinetics of Lidocaine Hydrochloride Administered with or without Adrenaline for the Paravertebral Brachial Plexus Block in Dogs

Adrenaline is known to prolong the duration of local anesthesia but its effects on the pharmacokinetic processes of local anesthetic drugs are not fully understood. Our objective was to develop a compartmental model for quantification of adrenaline’s impact on the pharmacokinetics of perineurally-in...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Choquette, Amélie, Troncy, Eric, Guillot, Martin, Varin, France, del Castillo, Jérôme R. E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221883/
https://ncbi.nlm.nih.gov/pubmed/28068408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169745
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