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CpG Island Methylator Phenotype-High Colorectal Cancers and Their Prognostic Implications and Relationships with the Serrated Neoplasia Pathway

The concept of a CpG island methylator phenotype (CIMP) was first introduced by Toyota and Issa to describe a subset of colorectal cancers (CRCs) with concurrent hypermethylation of multiple CpG island loci. The concept of CIMP as a molecular carcinogenesis mechanism was consolidated by the identifi...

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Udgivet i:Gut Liver
Main Authors: Rhee, Ye-Young, Kim, Kyung-Ju, Kang, Gyeong Hoon
Format: Artigo
Sprog:Inglês
Udgivet: Editorial Office of Gut and Liver 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221859/
https://ncbi.nlm.nih.gov/pubmed/27885175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5009/gnl15535
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