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Extending the dynamic range of transcription factor action by translational regulation

A crucial step in the regulation of gene expression is binding of transcription factor (TF) proteins to regulatory sites along the DNA. But transcription factors act at nanomolar concentrations, and noise due to random arrival of these molecules at their binding sites can severely limit the precisio...

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Detalhes bibliográficos
Publicado no:Phys Rev E
Main Authors: Sokolowski, Thomas R., Walczak, Aleksandra M., Bialek, William, Tkačik, Gašper
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221721/
https://ncbi.nlm.nih.gov/pubmed/26986359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1103/PhysRevE.93.022404
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