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BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death.

The BCL2 protooncogene encodes an inner mitochondrial membrane protein that blocks programmed cell death. BCL2 was isolated from the chromosomal breakpoint of follicular B-cell lymphoma. Transgenic mice that overexpress BCL2 display extended survival of resting B cells. In this study we use a monosp...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Hockenbery, D M, Zutter, M, Hickey, W, Nahm, M, Korsmeyer, S J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52213/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1871110/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.16.6961
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