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Novel germline mutations in FLCN gene identified in two Chinese patients with Birt–Hogg–Dubé syndrome

Birt–Hogg–Dubé (BHD) syndrome, a hereditary renal cancer syndrome caused by mutations in the folliculin (FLCN) gene, is characterized by the presence of fibrofolliculomas, pulmonary cysts, spontaneous pneumothorax, and renal cell carcinoma (RCC). Few BHD syndrome cases have been reported in Asian co...

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Bibliografiske detaljer
Udgivet i:Chin J Cancer
Main Authors: Li, Teng, Ning, Xianghui, He, Qun, Gong, Kan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5220607/
https://ncbi.nlm.nih.gov/pubmed/28069055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40880-016-0172-5
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