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Novel germline mutations in FLCN gene identified in two Chinese patients with Birt–Hogg–Dubé syndrome

Birt–Hogg–Dubé (BHD) syndrome, a hereditary renal cancer syndrome caused by mutations in the folliculin (FLCN) gene, is characterized by the presence of fibrofolliculomas, pulmonary cysts, spontaneous pneumothorax, and renal cell carcinoma (RCC). Few BHD syndrome cases have been reported in Asian co...

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Podrobná bibliografie
Vydáno v:Chin J Cancer
Hlavní autoři: Li, Teng, Ning, Xianghui, He, Qun, Gong, Kan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5220607/
https://ncbi.nlm.nih.gov/pubmed/28069055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40880-016-0172-5
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