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Celastrol ameliorates liver metabolic damage caused by a high-fat diet through Sirt1

OBJECTIVE: Celastrol was recently identified as a potential novel treatment for obesity. However, the effect of Celastrol on nonalcoholic fatty liver disease (NAFLD) remains elusive. The aim of this study is to evaluate the role of Celastrol in NAFLD. METHODS: Functional studies were performed using...

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Publicat a:Mol Metab
Autors principals: Zhang, Yinliang, Geng, Chao, Liu, Xiaoyan, Li, Meixia, Gao, Mingyue, Liu, Xiaojun, Fang, Fude, Chang, Yongsheng
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5220393/
https://ncbi.nlm.nih.gov/pubmed/28123944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.11.002
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