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Celastrol ameliorates liver metabolic damage caused by a high-fat diet through Sirt1

OBJECTIVE: Celastrol was recently identified as a potential novel treatment for obesity. However, the effect of Celastrol on nonalcoholic fatty liver disease (NAFLD) remains elusive. The aim of this study is to evaluate the role of Celastrol in NAFLD. METHODS: Functional studies were performed using...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Zhang, Yinliang, Geng, Chao, Liu, Xiaoyan, Li, Meixia, Gao, Mingyue, Liu, Xiaojun, Fang, Fude, Chang, Yongsheng
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5220393/
https://ncbi.nlm.nih.gov/pubmed/28123944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.11.002
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