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Analgesic and Anti-Inflammatory Effects of the Novel Semicarbazide-Sensitive Amine-Oxidase Inhibitor SzV-1287 in Chronic Arthritis Models of the Mouse

Semicarbazide-sensitive amine oxidase (SSAO) catalyses oxidative deamination of primary amines. Since there is no data about its function in pain and arthritis mechanisms, we investigated the effects of our novel SSAO inhibitor SzV-1287 in chronic mouse models of joint inflammation. Effects of SzV-1...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Horváth, Ádám, Menghis, Awt, Botz, Bálint, Borbély, Éva, Kemény, Ágnes, Tékus, Valéria, Csepregi, Janka Zsófia, Mócsai, Attila, Juhász, Tamás, Zákány, Róza, Bogdán, Dóra, Mátyus, Péter, Keeble, Julie, Pintér, Erika, Helyes, Zsuzsanna
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5220351/
https://ncbi.nlm.nih.gov/pubmed/28067251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39863
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