Blood transfusion during radical chemo-radiotherapy does not reduce tumour hypoxia in squamous cell cancer of the head and neck

BACKGROUND: Patients with head and neck squamous cell carcinoma (HNSCC) undergoing radical chemo-radiation (CRT) frequently receive transfusion with packed red cells (PRCT) during radiotherapy on the basis that PRCT increases tumour oxygenation and overcomes hypoxia-induced radio-resistance. This is...

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Detalles Bibliográficos
Publicado en:Br J Cancer
Autores principales: Welsh, Liam, Panek, Rafal, Riddell, Angela, Wong, Kee, Leach, Martin O, Tavassoli, Mahvash, Rahman, Durdana, Schmidt, Maria, Hurley, Tara, Grove, Lorna, Richards, Thomas, Koh, Dow-Mu, Nutting, Christopher, Harrington, Kevin, Newbold, Kate, Bhide, Shreerang
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2017
Materias:
Clinical Study
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5220150/
https://ncbi.nlm.nih.gov/pubmed/27884018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.386
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