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Distinct endothelial phenotypes evoked by arterial waveforms derived from atherosclerosis-susceptible and -resistant regions of human vasculature

Atherosclerotic lesion localization to regions of disturbed flow within certain arterial geometries, in humans and experimental animals, suggests an important role for local hemodynamic forces in atherogenesis. To explore how endothelial cells (EC) acquire functional/dysfunctional phenotypes in resp...

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Detalhes bibliográficos
Main Authors: Dai, Guohao, Kaazempur-Mofrad, Mohammad R., Natarajan, Sripriya, Zhang, Yuzhi, Vaughn, Saran, Blackman, Brett R., Kamm, Roger D., García-Cardeña, Guillermo, Gimbrone, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC522013/
https://ncbi.nlm.nih.gov/pubmed/15466704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406073101
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