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Hemodynamic Environments from Opposing Sides of Human Aortic Valve Leaflets Evoke Distinct Endothelial Phenotypes In Vitro

The regulation of valvular endothelial phenotypes by the hemodynamic environments of the human aortic valve is poorly understood. The nodular lesions of calcific aortic stenosis (CAS) develop predominantly beneath the aortic surface of the valve leaflets in the valvular fibrosa layer. However, the m...

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Detalhes bibliográficos
Main Authors: Weinberg, Eli J., Mack, Peter J., Schoen, Frederick J., García-Cardeña, Guillermo, Kaazempur Mofrad, Mohammad R.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837826/
https://ncbi.nlm.nih.gov/pubmed/20107896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10558-009-9089-9
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