A universal telomerase RNA core structure includes structured motifs required for binding the telomerase reverse transcriptase protein

Telomerase synthesizes telomeric DNA by copying a short template sequence within its telomerase RNA component. We delineated nucleotides and base-pairings within a previously mapped central domain of the Saccharomyces cerevisiae telomerase RNA (TLC1) that are important for telomerase function and fo...

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Detalhes bibliográficos
Main Authors: Lin, Jue, Ly, Hinh, Hussain, Arif, Abraham, Mira, Pearl, Sivan, Tzfati, Yehuda, Parslow, Tristram G., Blackburn, Elizabeth H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC522012/
https://ncbi.nlm.nih.gov/pubmed/15371596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405879101
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