Oxidative stress, mitochondrial abnormalities and antioxidant defense in Ataxia-telangiectasia, Bloom syndrome and Nijmegen breakage syndrome

Rare pleiotropic genetic disorders, Ataxia-telangiectasia (A-T), Bloom syndrome (BS) and Nijmegen breakage syndrome (NBS) are characterised by immunodeficiency, extreme radiosensitivity, higher cancer susceptibility, premature aging, neurodegeneration and insulin resistance. Some of these functional...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Maciejczyk, Mateusz, Mikoluc, Bozena, Pietrucha, Barbara, Heropolitanska - Pliszka, Edyta, Pac, Malgorzata, Motkowski, Radosław, Car, Halina
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5219618/
https://ncbi.nlm.nih.gov/pubmed/28063379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.12.030
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