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T Lymphocytes in Patients With Nijmegen Breakage Syndrome Demonstrate Features of Exhaustion and Senescence in Flow Cytometric Evaluation of Maturation Pathway

Patients with Nijmegen Breakage Syndrome (NBS) suffer from recurrent infections due to humoral and cellular immune deficiency. Despite low number of T lymphocytes and their maturation defect, the clinical manifestations of cell-mediated deficiency are not as severe as in case of patients with other...

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Bibliografische gegevens
Gepubliceerd in:Front Immunol
Hoofdauteurs: Piatosa, Barbara, Wolska-Kuśnierz, Beata, Tkaczyk, Katarzyna, Heropolitanska-Pliszka, Edyta, Grycuk, Urszula, Wakulinska, Anna, Gregorek, Hanna
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7338427/
https://ncbi.nlm.nih.gov/pubmed/32695108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01319
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