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Regulatory potential and control of Foxp3 expression in newborn CD4(+) T cells
Thymectomy at day 3 after birth leads to autoimmune disease in some genetic backgrounds. Disease is thought to be caused by the lack/paucity of regulatory T cells. We show that 3-day-old mice already contain a significant compartment of Foxp3-expressing CD25(+)CD4(+) splenocytes. Whereas, in adult s...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC521951/ https://ncbi.nlm.nih.gov/pubmed/15452347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403303101 |
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