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Suppression of CD4(+) Effector Responses by Naturally Occurring CD4(+) CD25(+) Foxp3(+) Regulatory T Cells Contributes to Experimental Cerebral Malaria

The role of naturally occurring CD4(+) CD25(+) Foxp3(+) regulatory T cells (nTreg) in the pathogenesis of cerebral malaria (CM), which involves both pathogenic T cell responses and parasite sequestration in the brain, is still unclear. To assess the contribution and dynamics of nTreg during the neur...

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Bibliographische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Blanc, Anne-Laurence, Keswani, Tarun, Gorgette, Olivier, Bandeira, Antonio, Malissen, Bernard, Cazenave, Pierre-André, Pied, Sylviane
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694001/
https://ncbi.nlm.nih.gov/pubmed/26553468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00717-15
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