Functional Human Oocytes Generated by Transfer of Polar Body Genomes

Oocyte defects lie at the heart of some forms of infertility, and could potentially be addressed therapeutically by alternative routes for oocyte formation. Here, we describe the generation of functional human oocytes following nuclear transfer of first polar body (PB1) genomes from metaphase II (MI...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Ma, Hong, O’Neil, Ryan C., Gutierrez, Nuria Marti, Hariharan, Manoj, Zhang, Zhuzhu Z., He, Yupeng, Cinnioglu, Cengiz, Kayali, Refik, Kang, Eunju, Lee, Yeonmi, Hayama, Tomonari, Koski, Amy, Nery, Joseph, Castanon, Rosa, Tippner-Hedges, Rebecca, Ahmed, Riffat, Van Dyken, Crystal, Li, Ying, Olson, Susan, Battaglia, David, Lee, David M., Wu, Diana H., Amato, Paula, Wolf, Don P., Ecker, Joseph R., Mitalipov, Shoukhrat
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5218919/
https://ncbi.nlm.nih.gov/pubmed/27840020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.10.001
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