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Activity-based targeting of secretory phospholipase A(2) enzymes: a fatty-acid-binding-protein assisted approach

Syntheses and enzymological characterization of fluorogenic substrate probes targeting secretory phospholipase A(2) (sPLA(2)) for detection and quantitative assays are presented. Three fluorogenic phosphatidylcholine analogs PC-1, PC-2, and PC-3 each containing the duo of 7-mercapto-4-methyl-coumari...

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Detalhes bibliográficos
Publicado no:Chem Phys Lipids
Main Authors: Keshavarz, Amir, Zelaya, Ligia, Singh, Jasmeet, Ranganathan, Radha, Hajdu, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5218917/
https://ncbi.nlm.nih.gov/pubmed/27894770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chemphyslip.2016.11.006
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