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Surface Dilution Kinetics Using Substrate Analog-Enantiomers as Diluents: Enzymatic Lipolysis by Bee-Venom Phospholipase A(2)

A novel assay employing D-enantiomers of phospholipids as diluents for characterizing surface kinetics of lipid hydrolysis by phospholipases is introduced. The rationale of the method are: (i) D-enantiomers resist hydrolysis because of the stereoselectivity of the enzymes toward L-enantiomers and (i...

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Main Authors: Singh, Jasmeet, Ranganathan, Radha, Hajdu, Joseph
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949497/
https://ncbi.nlm.nih.gov/pubmed/20727845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2010.08.015
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