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A constitutive intrinsic inflammatory signaling circuit composed of miR-196b, Meis2, PPP3CC, and p65, drives prostate cancer castration-resistance

Androgen deprivation therapy is the most effective treatment for advanced prostate cancer, however, almost all cancer eventually become castration-resistant, and the underlying mechanisms are largely unknown. Here, we show that an intrinsic constitutively activated feed-forward signaling circuit com...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Jeong, Ji-Hak, Park, Sun-Jin, Dickinson, Shohreh Iravani, Luo, Jun-Li
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5218896/
https://ncbi.nlm.nih.gov/pubmed/28041912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.11.034
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