Combination therapy of All-trans Retinoic Acid With Ursodeoxycholic Acid in Patients with Primary Sclerosing Cholangitis – A Human Pilot

GOALS: To perform an exploratory pilot study of all-trans retinoic acid (ATRA) combined with ursodeoxycholic acid (UDCA) in patients with primary sclerosing cholangitis (PSC). BACKGROUND: PSC is a progressive disorder for which there is no accepted therapy. Studies in human hepatocyte cultures and i...

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Udgivet i:J Clin Gastroenterol
Main Authors: Assis, David N., Abdelghany, Osama, Cai, Shi-Ying, Gossard, Andrea A., Eaton, John E., Keach, Jill C., Deng, Yanhong, Setchell, Kenneth D. R., Ciarleglio, Maria, Lindor, Keith D., Boyer, James L.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5218875/
https://ncbi.nlm.nih.gov/pubmed/27428727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MCG.0000000000000591
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