High-Dose Ursodeoxycholic Acid Is Associated With the Development of Colorectal Neoplasia in Patients With Ulcerative Colitis and Primary Sclerosing Cholangitis

OBJECTIVES: Some studies have suggested that ursodeoxycholic acid (UDCA) may have a chemopreventive effect on the development of colorectal neoplasia in patients with ulcerative colitis (UC) and primary sclerosing cholangitis (PSC). We examined the effects of high-dose (28–30 mg/kg/day) UDCA on the...

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Main Authors: Eaton, John E., Silveira, Marina G., Pardi, Darrell S., Sinakos, Emmanouil, Kowdley, Kris V., Luketic, Velimir A.C., Harrison, M. Edwyn, McCashland, Timothy, Befeler, Alex S., Harnois, Denise, Jorgensen, Roberta, Petz, Jan, Lindor, Keith D.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3168684/
https://ncbi.nlm.nih.gov/pubmed/21556038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajg.2011.156
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