High-Dose Ursodeoxycholic Acid Is Associated With the Development of Colorectal Neoplasia in Patients With Ulcerative Colitis and Primary Sclerosing Cholangitis

OBJECTIVES: Some studies have suggested that ursodeoxycholic acid (UDCA) may have a chemopreventive effect on the development of colorectal neoplasia in patients with ulcerative colitis (UC) and primary sclerosing cholangitis (PSC). We examined the effects of high-dose (28–30 mg/kg/day) UDCA on the...

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Main Authors: Eaton, John E., Silveira, Marina G., Pardi, Darrell S., Sinakos, Emmanouil, Kowdley, Kris V., Luketic, Velimir A.C., Harrison, M. Edwyn, McCashland, Timothy, Befeler, Alex S., Harnois, Denise, Jorgensen, Roberta, Petz, Jan, Lindor, Keith D.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3168684/
https://ncbi.nlm.nih.gov/pubmed/21556038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajg.2011.156
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