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High-Dose Ursodeoxycholic Acid Is Associated With the Development of Colorectal Neoplasia in Patients With Ulcerative Colitis and Primary Sclerosing Cholangitis

OBJECTIVES: Some studies have suggested that ursodeoxycholic acid (UDCA) may have a chemopreventive effect on the development of colorectal neoplasia in patients with ulcerative colitis (UC) and primary sclerosing cholangitis (PSC). We examined the effects of high-dose (28–30 mg/kg/day) UDCA on the...

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Bibliografische gegevens
Hoofdauteurs: Eaton, John E., Silveira, Marina G., Pardi, Darrell S., Sinakos, Emmanouil, Kowdley, Kris V., Luketic, Velimir A.C., Harrison, M. Edwyn, McCashland, Timothy, Befeler, Alex S., Harnois, Denise, Jorgensen, Roberta, Petz, Jan, Lindor, Keith D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3168684/
https://ncbi.nlm.nih.gov/pubmed/21556038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajg.2011.156
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