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Combinations of Adefovir with Nucleoside Analogs Produce Additive Antiviral Effects against Hepatitis B Virus In Vitro

Combination therapies may be required for long-term management of some patients chronically infected with hepatitis B virus (HBV). Adefovir is a nucleotide analog that has similar activity against wild-type and lamivudine-resistant HBV. In contrast to lamivudine, clinical resistance to the prodrug a...

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Publicado en:Antimicrob Agents Chemother
Principais autores: Delaney, William E., Yang, Huiling, Miller, Michael D., Gibbs, Craig S., Xiong, Shelly
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2004
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC521873/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15388423/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.10.3702-3710.2004
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