The Antiparasitic Compound Licochalcone A Is a Potent Echinocytogenic Agent That Modifies the Erythrocyte Membrane in the Concentration Range Where Antiplasmodial Activity Is Observed

The well-known antiparasitic compound licochalcone A is a potent membrane-active agent that transforms normal erythrocytes into echinocytes in parallel with the inhibition of growth of Plasmodium falciparum cultures, the in vitro antiplasmodial effect apparently being an indirect effect on the host...

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Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Ziegler, Hanne L., Hansen, Harald S., Stœrk, Dan, Christensen, Søren Brøgger, Hägerstrand, Henry, Jaroszewski, Jerzy W.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2004
Sujets:
Mechanisms of Action: Physiological Effects
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC521868/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15388483/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.10.4067-4071.2004
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