The Antiparasitic Compound Licochalcone A Is a Potent Echinocytogenic Agent That Modifies the Erythrocyte Membrane in the Concentration Range Where Antiplasmodial Activity Is Observed

The well-known antiparasitic compound licochalcone A is a potent membrane-active agent that transforms normal erythrocytes into echinocytes in parallel with the inhibition of growth of Plasmodium falciparum cultures, the in vitro antiplasmodial effect apparently being an indirect effect on the host...

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Detalhes bibliográficos
Main Authors: Ziegler, Hanne L., Hansen, Harald S., Stœrk, Dan, Christensen, Søren Brøgger, Hägerstrand, Henry, Jaroszewski, Jerzy W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC521868/
https://ncbi.nlm.nih.gov/pubmed/15388483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.10.4067-4071.2004
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