In Vitro Plasmodium falciparum Drug Sensitivity Assay: Inhibition of Parasite Growth by Incorporation of Stomatocytogenic Amphiphiles into the Erythrocyte Membrane

Lupeol, which shows in vitro inhibitory activity against Plasmodium falciparum 3D7 strain with a 50% inhibitory concentration (IC(50)) of 27.7 ± 0.5 μM, was shown to cause a transformation of the human erythrocyte shape toward that of stomatocytes. Good correlation between the IC(50) value and the m...

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Detalhes bibliográficos
Main Authors: Ziegler, Hanne L., Stærk, Dan, Christensen, Jette, Hviid, Lars, Hägerstrand, Henry, Jaroszewski, Jerzy W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Analytical Procedures
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127196/
https://ncbi.nlm.nih.gov/pubmed/11959580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.5.1441-1446.2002
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