Wnt Signaling Prevents the Aβ Oligomer-Induced Mitochondrial Permeability Transition Pore Opening Preserving Mitochondrial Structure in Hippocampal Neurons

Alzheimer’s disease (AD) is a neurodegenerative disorder mainly known for synaptic impairment and neuronal cell loss, affecting memory processes. Beside these damages, mitochondria have been implicated in the pathogenesis of AD through the induction of the mitochondrial permeability transition pore...

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發表在:PLoS One
Main Authors: Arrázola, Macarena S., Ramos-Fernández, Eva, Cisternas, Pedro, Ordenes, Daniela, Inestrosa, Nibaldo C.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2017
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5218554/
https://ncbi.nlm.nih.gov/pubmed/28060833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168840
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