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Wnt Signaling Prevents the Aβ Oligomer-Induced Mitochondrial Permeability Transition Pore Opening Preserving Mitochondrial Structure in Hippocampal Neurons

Alzheimer’s disease (AD) is a neurodegenerative disorder mainly known for synaptic impairment and neuronal cell loss, affecting memory processes. Beside these damages, mitochondria have been implicated in the pathogenesis of AD through the induction of the mitochondrial permeability transition pore...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Arrázola, Macarena S., Ramos-Fernández, Eva, Cisternas, Pedro, Ordenes, Daniela, Inestrosa, Nibaldo C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5218554/
https://ncbi.nlm.nih.gov/pubmed/28060833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168840
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