Wnt Signaling Prevents the Aβ Oligomer-Induced Mitochondrial Permeability Transition Pore Opening Preserving Mitochondrial Structure in Hippocampal Neurons

Alzheimer’s disease (AD) is a neurodegenerative disorder mainly known for synaptic impairment and neuronal cell loss, affecting memory processes. Beside these damages, mitochondria have been implicated in the pathogenesis of AD through the induction of the mitochondrial permeability transition pore...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Arrázola, Macarena S., Ramos-Fernández, Eva, Cisternas, Pedro, Ordenes, Daniela, Inestrosa, Nibaldo C.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5218554/
https://ncbi.nlm.nih.gov/pubmed/28060833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168840
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