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Positioning of Tacrolimus for the Treatment of Diabetic Nephropathy Based on Computational Network Analysis

OBJECTIVE: To evaluate tacrolimus as therapeutic option for diabetic nephropathy (DN) based on molecular profile and network-based molecular model comparisons. MATERIALS AND METHODS: We generated molecular models representing pathophysiological mechanisms of DN and tacrolimus mechanism of action (Mo...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Aschauer, Constantin, Perco, Paul, Heinzel, Andreas, Sunzenauer, Judith, Oberbauer, Rainer
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217951/
https://ncbi.nlm.nih.gov/pubmed/28060893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169518
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