Proteome Profiling Outperforms Transcriptome Profiling for Coexpression Based Gene Function Prediction

Coexpression of mRNAs under multiple conditions is commonly used to infer cofunctionality of their gene products despite well-known limitations of this “guilt-by-association” (GBA) approach. Recent advancements in mass spectrometry-based proteomic technologies have enabled global expression profilin...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Mol Cell Proteomics
Autori principali: Wang, Jing, Ma, Zihao, Carr, Steven A., Mertins, Philipp, Zhang, Hui, Zhang, Zhen, Chan, Daniel W., Ellis, Matthew J. C., Townsend, R. Reid, Smith, Richard D., McDermott, Jason E., Chen, Xian, Paulovich, Amanda G., Boja, Emily S., Mesri, Mehdi, Kinsinger, Christopher R., Rodriguez, Henry, Rodland, Karin D., Liebler, Daniel C., Zhang, Bing
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2017
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217778/
https://ncbi.nlm.nih.gov/pubmed/27836980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M116.060301
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