Proteome Profiling Outperforms Transcriptome Profiling for Coexpression Based Gene Function Prediction

Coexpression of mRNAs under multiple conditions is commonly used to infer cofunctionality of their gene products despite well-known limitations of this “guilt-by-association” (GBA) approach. Recent advancements in mass spectrometry-based proteomic technologies have enabled global expression profilin...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Wang, Jing, Ma, Zihao, Carr, Steven A., Mertins, Philipp, Zhang, Hui, Zhang, Zhen, Chan, Daniel W., Ellis, Matthew J. C., Townsend, R. Reid, Smith, Richard D., McDermott, Jason E., Chen, Xian, Paulovich, Amanda G., Boja, Emily S., Mesri, Mehdi, Kinsinger, Christopher R., Rodriguez, Henry, Rodland, Karin D., Liebler, Daniel C., Zhang, Bing
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217778/
https://ncbi.nlm.nih.gov/pubmed/27836980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M116.060301
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