Chargement en cours...

Discovery of Enzymatic Targets of Transcriptional Activators via in Vivo Covalent Chemical Capture

The network of activator protein-protein interactions (PPIs) that underpin transcription initiation is poorly defined, particularly in the cellular context. The transient nature of these contacts and the often low abundance of the participants present significant experimental hurdles. Through the co...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Am Chem Soc
Auteurs principaux: Dugan, Amanda, Majmudar, Chinmay Y., Pricer, Rachel, Niessen, Sherry, Lancia, Jody K., Fung, Hugo Yik-Hong, Cravatt, Benjamin F., Mapp, Anna K.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217703/
https://ncbi.nlm.nih.gov/pubmed/27611834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b07680
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!