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Discovery of Enzymatic Targets of Transcriptional Activators via in Vivo Covalent Chemical Capture
The network of activator protein-protein interactions (PPIs) that underpin transcription initiation is poorly defined, particularly in the cellular context. The transient nature of these contacts and the often low abundance of the participants present significant experimental hurdles. Through the co...
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Publicado no: | J Am Chem Soc |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5217703/ https://ncbi.nlm.nih.gov/pubmed/27611834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b07680 |
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