Versican Deficiency Significantly Reduces Lung Inflammatory Response Induced by Polyinosine-Polycytidylic Acid Stimulation

Viral infection is an exacerbating factor contributing to chronic airway diseases, such as asthma, via mechanisms that are still unclear. Polyinosine-polycytidylic acid (poly(I:C)), a Toll-like receptor 3 (TLR3) agonist used as a mimetic to study viral infection, has been shown to elicit inflammator...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Kang, Inkyung, Harten, Ingrid A., Chang, Mary Y., Braun, Kathleen R., Sheih, Alyssa, Nivison, Mary P., Johnson, Pamela Y., Workman, Gail, Kaber, Gernot, Evanko, Stephen P., Chan, Christina K., Merrilees, Mervyn J., Ziegler, Steven F., Kinsella, Michael G., Frevert, Charles W., Wight, Thomas N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Glycobiology and Extracellular Matrices
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217699/
https://ncbi.nlm.nih.gov/pubmed/27895126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.753186
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