Versican Deficiency Significantly Reduces Lung Inflammatory Response Induced by Polyinosine-Polycytidylic Acid Stimulation

Viral infection is an exacerbating factor contributing to chronic airway diseases, such as asthma, via mechanisms that are still unclear. Polyinosine-polycytidylic acid (poly(I:C)), a Toll-like receptor 3 (TLR3) agonist used as a mimetic to study viral infection, has been shown to elicit inflammator...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kang, Inkyung, Harten, Ingrid A., Chang, Mary Y., Braun, Kathleen R., Sheih, Alyssa, Nivison, Mary P., Johnson, Pamela Y., Workman, Gail, Kaber, Gernot, Evanko, Stephen P., Chan, Christina K., Merrilees, Mervyn J., Ziegler, Steven F., Kinsella, Michael G., Frevert, Charles W., Wight, Thomas N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217699/
https://ncbi.nlm.nih.gov/pubmed/27895126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.753186
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