Загрузка...
Interferons Induce Expression of SAMHD1 in Monocytes through Down-regulation of miR-181a and miR-30a
SAMHD1 is a phosphohydrolase maintaining cellular dNTP homeostasis but also acts as a critical regulator in innate immune responses due to its antiviral activity and association with autoimmune disease, leading to aberrant activation of interferon. SAMHD1 expression is differentially regulated by in...
Сохранить в:
| Опубликовано в: : | J Biol Chem |
|---|---|
| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2017
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5217685/ https://ncbi.nlm.nih.gov/pubmed/27909056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.752584 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|