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Identification of coding and non-coding mutational hotspots in cancer genomes

BACKGROUND: The identification of mutations that play a causal role in tumour development, so called “driver” mutations, is of critical importance for understanding how cancers form and how they might be treated. Several large cancer sequencing projects have identified genes that are recurrently mut...

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Vydáno v:BMC Genomics
Hlavní autoři: Piraino, Scott W., Furney, Simon J.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217664/
https://ncbi.nlm.nih.gov/pubmed/28056774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-3420-9
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