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Identification of coding and non-coding mutational hotspots in cancer genomes

BACKGROUND: The identification of mutations that play a causal role in tumour development, so called “driver” mutations, is of critical importance for understanding how cancers form and how they might be treated. Several large cancer sequencing projects have identified genes that are recurrently mut...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Piraino, Scott W., Furney, Simon J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217664/
https://ncbi.nlm.nih.gov/pubmed/28056774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-3420-9
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