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AXL receptor tyrosine kinase as a therapeutic target in NSCLC

The AXL receptor tyrosine kinase and its ligand, Gas6, regulate key processes in lung cancer growth, metastasis, and epithelial–mesenchymal transition-associated drug resistance. Gas6 and AXL expression have been correlated with poor prognosis and advanced clinical stage in patients with lung cancer...

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Detalles Bibliográficos
Publicado en:Lung Cancer (Auckl)
Autores principales: Okimoto, Ross A, Bivona, Trever G
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217513/
https://ncbi.nlm.nih.gov/pubmed/28210148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/LCTT.S60438
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