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Targeted treatment of mutated EGFR-expressing non-small-cell lung cancer: focus on erlotinib with companion diagnostics

Deeper understanding of the pathobiology of non-small-cell lung cancer (NSCLC) has led to the development of small molecules that target genetic mutations known to play critical roles in the progression to metastatic disease. The discovery of epidermal growth factor receptor (EGFR) mutations in 15%–...

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Bibliografiske detaljer
Udgivet i:Lung Cancer (Auckl)
Main Authors: Karachaliou, Niki, Rosell, Rafael
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217512/
https://ncbi.nlm.nih.gov/pubmed/28210145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/LCTT.S50671
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