Targeting PKCι-PAK1 in EGFR-mutation positive non-small cell lung cancer

BACKGROUND: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) induce significant responses in EGFR-mutation positive non-small cell lung cancer (NSCLC). However, universal progression is observed. METHODS: The effect of the anti-rheumatoid agent, auranofin, a selective inhibi...

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Publicado en:Transl Lung Cancer Res
Autores principales: Ito, Masaoki, Codony-Servat, Carles, Karachaliou, Niki, Rosell, Rafael
Formato: Artigo
Lenguaje:Inglês
Publicado: AME Publishing Company 2019
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6835115/
https://ncbi.nlm.nih.gov/pubmed/31737502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tlcr.2019.08.25
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