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Protein-Ligand Electrostatic Binding Free Energies From Explicit and Implicit Solvation

Accurate yet efficient computational models of solvent environment are central for most calculations that rely on atomistic modeling, such as prediction of protein-ligand binding affinities. In this study, we evaluate the accuracy of a recently developed generalized Born implicit solvent model, GBNS...

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Bibliografiska uppgifter
I publikationen:J Chem Theory Comput
Huvudupphovsmän: Izadi, Saeed, Aguilar, Boris, Onufriev, Alexey V.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217485/
https://ncbi.nlm.nih.gov/pubmed/26575935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.5b00483
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