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Protein-Ligand Electrostatic Binding Free Energies From Explicit and Implicit Solvation

Accurate yet efficient computational models of solvent environment are central for most calculations that rely on atomistic modeling, such as prediction of protein-ligand binding affinities. In this study, we evaluate the accuracy of a recently developed generalized Born implicit solvent model, GBNS...

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Bibliografische gegevens
Gepubliceerd in:J Chem Theory Comput
Hoofdauteurs: Izadi, Saeed, Aguilar, Boris, Onufriev, Alexey V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217485/
https://ncbi.nlm.nih.gov/pubmed/26575935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jctc.5b00483
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