CD36 Deficiency Impairs the Small Intestinal Barrier and Induces Subclinical Inflammation in Mice

BACKGROUND & AIMS: CD36 has immunometabolic actions and is abundant in the small intestine on epithelial, endothelial, and immune cells. We examined the role of CD36 in gut homeostasis by using mice null for CD36 (CD36KO) and with CD36 deletion specific to enterocytes (Ent-CD36KO) or endothelial...

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Vydáno v:Cell Mol Gastroenterol Hepatol
Hlavní autoři: Cifarelli, Vincenza, Ivanov, Stoyan, Xie, Yan, Son, Ni-Huiping, Saunders, Brian T., Pietka, Terri A., Shew, Trevor M., Yoshino, Jun, Sundaresan, Sinju, Davidson, Nicholas O., Goldberg, Ira J., Gelman, Andrew E., Zinselmeyer, Bernd H., Randolph, Gwendalyn J., Abumrad, Nada A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2016
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217470/
https://ncbi.nlm.nih.gov/pubmed/28066800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2016.09.001
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